• Association between type I interferon pathway activation and clinical outcomes in rheumatic and musculoskeletal diseases: a systematic literature review informing EULAR points to consider 

      Rodríguez-Carrio, Javier; Burska, Agata; Conaghan, P.G.; Dik, Willem A; Biesen, Robert; Eloranta, Maija-Leena; Cavalli, Giulio; Visser, Marianne; Boumpas, Dimitrios T; Bertsias, George; Wahren Herlenius, Marie Elisabeth; Rehwinkel, Jan; Frémond, Marie-Louise; Crow, Mary K; Ronnblom, Lars; Vital, Ed; Versnel, Marjan (Journal article; Peer reviewed, 2023)
      Background: Type I interferons (IFN-I) contribute to a broad range of rheumatic and musculoskeletal diseases (RMDs). Compelling evidence suggests that the measurement of IFN-I pathway activation may have clinical value. ...
    • PARP14 is a PARP with both ADP-ribosyl transferase and hydrolase activities 

      Đukić, Nina; Strømland, Øyvind; Elsborg, Jonas Damgaard; Munnur, Deeksha; Zhu, Kang; Schuller, Marion; Chatrin, Chatrin; Kar, Pulak; Duma, Lena; Suyari, Osamu; Rack, Johannes Gregor Matthias; Baretić, Domagoj; Crudgington, Dorian Richard Kenneth; Groslambert, Joséphine; Fowler, Gerissa; Wijngaarden, Sven; Prokhorova, Evgeniia; Rehwinkel, Jan; Schüler, Herwig; Filippov, Dmitri V.; Sanyal, Sumana; Ahel, Dragana; Nielsen, Michael L.; Smith, Rebecca; Ahel, Ivan (Journal article; Peer reviewed, 2023)
      PARP14 is a mono–ADP-ribosyl transferase involved in the control of immunity, transcription, and DNA replication stress management. However, little is known about the ADP-ribosylation activity of PARP14, including its ...
    • Type I interferon pathway assays in studies of rheumatic and musculoskeletal diseases: a systematic literature review informing EULAR points to consider 

      Burska, Agata; Rodríguez-Carrio, Javier; Biesen, Robert; Dik, Willem A.; Eloranta, Maija-Leena; Cavalli, Giulio; Visser, Marianne; Boumpas, Dimitrios T.; Bertsias, George; Wahren Herlenius, Marie Elisabeth; Rehwinkel, Jan; Frémond, Marie-Louise; Crow, Mary K.; Ronnblom, Lars; Conaghan, P.G.; Versnel, Marjan; Vital, Ed (Journal article; Peer reviewed, 2023)
      Objectives: To systematically review the literature for assay methods that aim to evaluate type I interferon (IFN-I) pathway activation and to harmonise-related terminology. Methods: Three databases were searched for ...